PQQ, considered a novel cofactor with antioxidant and B vitamin-like activity, supports mitochondrial function.* PQQ and CoQ10 work together to promote antioxidant activity and mitochondrial health, providing multifunctional support for cardiovascular and neuro health.* BioPQQ is manufactured in Japan using a patented fermentation process. Natural Factors CoQ10 is also produced through fermentation, consisting only of the natural form trans isomer identical to the body’s own CoQ10.