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Scientifically studied ingredients for healthy sleep
Lemon Balm: In one study, 85% of subjects who took lemon balm extract for 15 days saw a significant improvement in healthy sleep and the remaining 15% were much improved.8
Honokiol: Pre-clinical models indicate honokiol is quickly taken up into the brain, making it an ideal ingredient for those looking for a well-deserved rest.9-11 Honokiol has a calming effect on the brain as well.
Chamomile: Computer models and pre-clinical studies suggest apigenin might promote healthy sleep patterns similar to those caused by naturally-occurring neurologically active compounds in the body.12,13
References:
1. Soc Sci Med. 2007;64(10):1997-2007.
2. Mol Vis. 2016;22:61-72.
3. Int J Behav Med. 2017;24(4):481-492.
4. Prog Cardiovasc Nurs. 2004;19(2):56-9.
5. Neuropsychiatr Dis Treat. 2007;3(5):553-67.
6. Obes Rev. 2009;10(Suppl 2):37-45.
7. Curr Cardiol Rev. 2010;6(1):54-61.
8. Med J Nutrition Metab. 2011;4(3):211-218.
9. Br J Pharmacol. 2012;167(3):587-98.
10. J Pharm Pharmacol. 1999;51(1):97-103.
11. Eur J Drug Metab Pharmacokinet. 2016;41(5):587-94.
12. Fitoterapia. 2000;71(Suppl. 1):S117-S123.
13. Data on File. Connectivity Map (CMAP) Analysis. 2018.
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