The GI tract is a finely balanced environment where roughly 500 different strains of bacteria compete for space and nutrients. When there is a healthy balance (eubiosis), few symptoms exist. However, dysbiosis can occur when an overabundance of potentially harmful organisms prevail. The natural microflora balance can be upset by medications (such as antibiotics, oral contraceptives, etc.), excessive alcohol consumption, or poor dietary intake.
Because probiotics are live organisms, there are many challenges associated with manufacturing and distributing probiotic supplements. For a probiotic to be effective, it must be shelf-stable through the expiration date and precisely delivered to the intestinal tract, where it can have maximum benefit. The microorganisms in Ortho Biotic are protected, sealed and freeze dried away from moisture, heat, light and oxygen. This allows the bacteria to remain dormant until they are exposed to moisture in the GI tract.
Ortho Biotic® is a unique probiotic formula designed to deliver active organisms shown to promote healthy gut flora, protect intestinal integrity and boost immune function. Included in this formula isSaccharomyces boulardii, an extensively researched microorganism shown to help restore microflora balance by enhancing commensal organisms. Each scoop of Ortho Biotic provides seven proven probiotic strains chosen for their ability to withstand the harsh gastrointestinal (GI) environment and adhere to the intestinal tract, and deliver superior results. Ortho Biotic is also available in capsules at the same high concentration for those who prefer capsule delivery.
1 scoop (1.7 g) per day or as recommended by your health care professional.
Guaranteed potency at expiration. No refrigeration required.
Lactobacillus acidophilusis a beneficial bacterial strain that is normally found in the intestinal tract and mouth and is commercially used in dairy products for the production of acidophilus-type yogurt.L. acidophilusferments various carbohydrates to produce lactic acid, which increases the absorption and bioavailability of minerals. This includes calcium, copper, magnesium and manganese. The production of lactic acid also promotes health by creating an inhospitable environment for invading microbes.L. acidophilushas been shown to protect intestinal cells by competing for adhesion space in the gut against harmful bacteria, such asE. coli. TheL. acidophilusstrain in Ortho Biotic has been specifically chosen because of its strong adherence and survival attributes in the GI tract. It has been demonstrated in vitro to tolerate exposure to gastric acid and bile salts, and has the ability to withstand antibiotics including Ciproflaxin, Polymyxin B and Tetracycline.
Lactobacillus paracaseihas been shown to protect against the harmful effects of bacteria such asStaphylococcus aureus(S. aureus).L. paracaseicolonizes the intestinal tract by reinforcing defense mechanisms that support an immune response. It does this by supporting T-helper cell production and secreting secretory IgA (sIgA), an antibody critical for supporting intestinal immunity.L. paracaseiLpc-37 is a gastric acid-resistant strain and has been shown in vitro to withstand antibiotics such as Ciproflaxin and Vancomycin.
Bifidobacterium bifidumhas been shown to effectively compete with harmful bacteria such asE. coli,S. aureusandCamplylobacter jejuni, which suggestsB. bifidum’s lactic acid and acetic acid production provides an antagonistic action against pathogens to help maintain microflora balance.
Bifidobacterium lactisis predominantly found in the colon. A double-blind, randomized placebo-controlled trial on subjects receivingB. lactisor placebo for eight weeks found thatB. lactissupported a balanced immune response in individuals hypersensitive to environmental allergens. Studies examining immune development and dietary supplementation withB. lactishave shown that it supports GI health by reducing intestinal permeability.
Lactobacillus plantarumis a beneficial bacteria commonly found in fermented foods including sauerkraut, pickles, brined olives and sourdough.L. plantarumhas been found to compete against strains ofClostridium difficileandClostridium perfringens, due to the production of bacteriocins (lethal proteins) that inhibit bacterial growth. Studies have also demonstrated thatL. plantarumhelps boost the immune response by stimulating Th1-mediated immunity.
Lactobacillus rhamnosushas been proven to have remarkable survivability in the acid and bile environments in the GI tract.L. rhamnosusis particularly useful because of its ability to adhere to cells, enhance microflora balance, and inhibit pathogen adherence.L. rhamnosuswas also found to positively affect inflammatory and immune gene signaling of over 1,700 genes when administered in high doses.
Saccharomyces boulardiiis a probiotic yeast that was first isolated from the skin of the tropical fruits lychee and mangosteen in 1923 by French scientist Henri Boulard, following the observation that mangosteen consumption controlled occasional diarrhea in natives of Southeast Asia.S. boulardiiplays a role in supporting immune defense by increasing levels of sIgA, creating a first line of defense that helps bind and clear harmful bacteria.